HLA-G14bp insertion and the KIR2DS1-HLAC2 complex impact on behavioral impairment in children with autism spectrum disorders

FR Guerini, E Bolognesi, M Chiappedi, A Ghezzo… - Neuroscience, 2018 - Elsevier
… We evaluated whether HLA-G14bp(+/−) and KIR-HLA-C complexes are associated with …
of KIR2DS1-HLAC2+/HLA-G14bp+ pattern with behavioral impairment in ASD children. …

HLA-G coding region polymorphism is skewed in autistic spectrum disorders

FR Guerini, E Bolognesi, M Chiappedi… - Brain, behavior, and …, 2018 - Elsevier
… onset of autistic spectrum disorders (ASD), we evaluated HLA G*01:… HLA-G14bp insertion
and the KIR2DS1-HLAC2 complex impact on behavioral impairment in children with Autism

Autism and KIR genes of the human genome: A brief meta-analysis

N Pirzadroozbahani, SAY Ahmadi, H Hekmat… - Egyptian Journal of …, 2018 - ajol.info
… significant based on fixed effect model (P = .028; OR = 1.31). Conclusions: Autism spectrum
disorders are accompanied by … HLA-G*14bp insertion and the KIR2DS1-HLAC2 complex

[HTML][HTML] Persistence of dysfunctional natural killer cells in adults with high-functioning autism spectrum disorders: stigma/consequence of unresolved early infectious …

M Bennabi, N Tarantino, A Gaman, I Scheid… - Molecular Autism, 2019 - Springer
… (KIR)/HLA complex that could promote immune activation in … may affect neurogenesis,
resulting in adverse consequences … -modulatory non-classical HLA-G was consistently found to …

HLA-G* 14 bp indel variant in autism spectrum disorder in a population from southern Brazil

M Ziliotto, B Kulmann-Leal, V de Lima Kaminski… - Journal of …, 2023 - Elsevier
… We aimed to assess the influence of the HLA-G*14 bp indel … The Human Leukocyte Antigen
system (HLA) is a complex of … between the 14*bp insertion in the 3’UTR of the HLA-G gene …

The Human Leukocyte Antigen System in Psychiatry: Where Do We Stand?

R Tamouza, R Krishnamoorthy, M Leboyer - Immuno-Psychiatry: Facts and …, 2021 - Springer
… /aberrant response of the MHC complex very likely plays a … the HLA genetic diversity and
autism spectrum disorders (ASD) … of both HLA-G polymorphism and expression in psychiatric …

[HTML][HTML] Immunogenetics of autism spectrum disorder: A systematic literature review

M Arenella, R Matuleviciute, R Tamouza… - Brain, Behavior, and …, 2023 - Elsevier
… The aetiology of autism spectrum disorder (ASD) is complex … HLA class I gene, HLA-G, a
strong immunomodulator which helps … the effect of immunogenetic variations in autistic females. …

[HTML][HTML] Understanding the genetic contribution of the human leukocyte antigen system to common major psychiatric disorders in a world pandemic context

R Tamouza, R Krishnamoorthy, M Leboyer - Brain, Behavior, and Immunity, 2021 - Elsevier
… The human leukocyte antigen (HLA) is a complex genetic system that encodes … HLA-G
polymorphism and/or expression in psychiatric disorders including Autism Spectrum Disorders

[HTML][HTML] Autism spectrum disorder from the womb to adulthood: Suggestions for a paradigm shift

C Panisi, FR Guerini, PM Abruzzo, F Balzola… - Journal of personalized …, 2021 - mdpi.com
… within the spectrum poses the difficult challenge in … suggested for non-classical HLA-G
polymorphisms in ASD mothers [111… effects [165] and attenuates social behavior deficits in autism

The contribution of inflammation to autism spectrum disorders: recent clinical evidence

J Prata, AS Machado, O von Doellinger… - Psychiatric Disorders …, 2019 - Springer
Autism comprises a complex and heterogeneous spectrum … of the disorder and the long-term
consequences of their use in … of the HLA-G alleles were increased in ASD children [54, 55]. …